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PULSe Home > Training Groups > Molecular Virology

Molecular Virology

Molecular Virology

Research Includes

  • Antiviral Drug Design Strategies
  • Antiviral Immunity
  • Gene Expression
  • Molecular Pathogenesis
  • Virus Assembly
  • Virus Structure
  • Virus-Host Interactions

  • Hot Topic

  • The Good Side of Viruses. Click HERE To Read More.

  • Training Group Mission

    The primary goal of the Molecular Virology group is to train the next generation of scientists interested in pursuing problems in virology and related disciplines. The program draws upon the vast diversity of scientific expertise at Purdue and allows students to receive broad experience in the field. Virologists at Purdue work in several areas that include virus structure and function, virus assembly, viral gene expression, antiviral drug development, virus vectors for gene delivery, recombinant virus vaccines, virus pathogenesis, viral genome analyses, and the development of virus-resistant transgenic plants. Students receive training in biochemical, molecular genetic, cell biological, and structural approaches to virus replication and control.

    Faculty Membership

    Faculty Research Area
    Anderson, Joseph M. Plant host-viral interactions; identification, characterization of molecular markers for resistance genes; cellular and functional genomics
    Andrisani, Ourania M. Transcription factor CREB (cAMP-response-element binding protein) in mechanisms of growth control and cellular differentiation
    Barton, Erik S. Understanding mechanisms of innate immunity during acute and latent herpesvirus infection
    Broyles, Steven S. Transcriptional regulation in poxviruses
    Chen, Jue ABC transporters and membrane fusion proteins
    Chmielewski, Jean A. Development of small molecules, peptides and peptidomimetics for drug discovery, bionanotechnology, and cellular delivery of therapeutic agents
    Cushman, Mark Design and synthesis of molecules that interact with enzymes and membrane-bound receptors
    Friedman, Alan Structural cell biology of infection, immunity, and aging
    Golden, Barbara Structural basis for RNA function
    Kirchmaier, Ann L. Epigenetic processes that mediate heritable modifications to chromatin
    Kuhn, Richard J. Viral gene expression; virus-host interactions; pathogenesis; virus receptors and virus assembly
    LaCount, Doug Systems biology of malaria parasites; protein-protein interactions
    Lin, Tsang Long Diagnostic pathology, molecular pathology and immunohistopathology of infectious, toxic and neoplastic diseases, animal pathology
    Loesch-Fries, Sue Molecular Virology - function of viral genes in virus replication, disease development, and virus control
    Post, Carol B. Computational chemistry and biological NMR
    Rossmann, Michael G. Structure of picornaviruses, parvoviruses, alphaviruses and bacteriophages, fX174, f29, T4; molecular evolution
    Sanders, David A. Entry of retroviruses and other enveloped viruses into cells; mechanism of enzymatic phosphoryl transfer
    Wu, Ching Ching Microbial pathogenesis; host-parasite interactions; molecular detection and differentiation of microbial pathogens; recombinant and DNA vaccines


    Student Membership

    Training Groups are topic-oriented research groups consisting of faculty from multiple departments. Training groups are an administrative home for PULSe students, a student choice that impacts curriculum and research training activities.

     

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