Drug studied as possible treatment for spinal injuries
Researchers have shown how an experimental drug might restore the function of nerves damaged in spinal cord injuries by preventing short circuits Read more...
New effort probes how two groups of viruses cause disease
Purdue University is leading a team of researchers in a federally funded effort aimed ultimately at developing better vaccines and antiviral drugs Read more...
Findings show nanomedicine promising for treating spinal cord injuries
Researchers at Purdue University have discovered a new approach for repairing damaged nerve fibers in spinal cord injuries using nano-spheres that Read more...
Enzyme may be a key to Alzheimer's-related cell death
A Purdue University researcher has discovered that the amount of an enzyme present in neurons can affect the mechanism thought to cause cell death Read more...
Protein helps cells duplicate correctly, avoid becoming cancer
A Purdue researcher has discovered that the absence of certain proteins needed for proper cell duplication can lead to Read more...
Purdue to dedicate Hockmeyer Hall of Structural Biology
Purdue University structural biologists - a group that provides insights that lead to vaccines and other disease treatments - are getting a booster Read more...
Dow AgroSciences, Purdue, IEDC partner for life sciences venture at Purdue Research Park
A new development project in the life sciences arena was announced Wednesday (Sept. 30) as part of a new agricultural collaboration among Dow Read more...
The central role of biomolecular structure and biophysics in life science research provides the rationale for a program in Biomolecular Structure and Biophysics, focussing on structures of key macromolecules and the understanding of their biological roles. The training group includes expertise in a variety of physical and computational approaches used to determine three-dimensional structure, to probe biophysical properties of biomolecules, and to predict structure/function relationships. Areas of strength include X-ray crystallography, NMR spectroscopy, electron microscopy, bioinformatics, computational biology and biophysics, chemical biology, enzymology, and biofluorescence spectroscopy.
Structure of tailed dsDNA bacteriophages and Flaviviruses; Membrane protein structure by 2-D crystallization; Cryo-EM method development; Large scale computing for cryo-EM image processing
bioinformatics and computational biology: Protein tertiary structure prediction, protein structure analysis, comparison, protein sequence analysis, protein function prediction, evolution of protein families
Development of targeted therapic and imaging agents for cancer and various inflammatory diseases. Function and molecular organization of the human red blood cell membrane. Novel methods for detection of human pathogens.
1) development of transiently-stable lipid- and polymer-based carrier systems for targeted drug & gene delivery; 2) development of high-throughput methods for detecting membrane protein activity; 3) development of materials and methods for controlled adsorption and templated protein crystallization
Training Groups are topic-oriented research groups consisting of faculty from multiple departments.
Training groups are an administrative home for PULSe students, a student choice that impacts
curriculum and research training activities.
