|
PULSe Home > Student Members > Maris Cinelli
Maris A. Cinelli
|
Graduate Research Assistant/PhD. Candidate
Department of Medicinal Chemistry and Molecular Pharmacology
B.S., Biology/Physiology, Northern Michigan University, 2006.
Contact Info:
mcinelli@purdue.edu
765-494-9778
Training Group(s):
Chemical Biology
|
Current Research Interests:
Design and synthesis of novel non-camptothecin topoisomerase 1 (Top1) inhibitors as potential anticancer agents; development of new synthetic routes and methodology.
Selected Publications:
1. Cinelli, M. A.; Morrell, A.; Dexheimer, T. S.; Scher, E. S.; Pommier, Y.; and Cushman, M. Design, Synthesis, and Biological Evaluation of 14-Substituted Aromathecins as Topoisomerase I Inhibitors. J. Med. Chem. 2008, 51(15), 4609-4619.
2. Cinelli, M. A.; Cordero, B.; Dexheimer, T.S.; Pommier, Y.; and Cushman, M. Synthesis and Biological Evaluation of 14-(Aminoalkyl-aminomethyl)aromathecins as Topoisomerase I Inhibitors: Investigating the Hypothesis of Shared Structure-Activity Relationships. Bioorg. Med. Chem. 2009, in press.
Other Interests:
NMR spectroscopy, nature and wildlife, insect collecting, writing poetry and prose, drawing, watching football, and just hanging out.
|